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Glutamine promotes O-GlcNAcylation of G6PD and inhibits AGR2 S-glutathionylation to maintain the intestinal mucus barrier in burned septic mice
Mucus forms the first line of defence of the intestinal mucosa barrier, and mucin is its core component. Glutamine is a vital energy substance for goblet cells; it can promote mucus synthesis and alleviate damage to the intestinal mucus barrier after burn injury, but its mechanism is not fully under...
Autores principales: | Wu, Dan, Su, Sen, Zha, Xule, Wei, Yan, Yang, Gang, Huang, Qianying, Yang, Yongjun, Xia, Lin, Fan, Shijun, Peng, Xi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800542/ https://www.ncbi.nlm.nih.gov/pubmed/36565645 http://dx.doi.org/10.1016/j.redox.2022.102581 |
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