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Adipose-derived mesenchymal stromal cells decrease prion-induced glial inflammation in vitro

Prion diseases are characterized by the cellular prion protein, PrP(C), misfolding and aggregating into the infectious prion protein, PrP(Sc), which leads to neurodegeneration and death. An early sign of disease is inflammation in the brain and the shift of resting glial cells to reactive astrocytes...

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Detalles Bibliográficos
Autores principales: Hay, Arielle J. D., Murphy, Tanner J., Popichak, Katriana A., Zabel, Mark D., Moreno, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800558/
https://www.ncbi.nlm.nih.gov/pubmed/36581683
http://dx.doi.org/10.1038/s41598-022-26628-7