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Adipose-derived mesenchymal stromal cells decrease prion-induced glial inflammation in vitro
Prion diseases are characterized by the cellular prion protein, PrP(C), misfolding and aggregating into the infectious prion protein, PrP(Sc), which leads to neurodegeneration and death. An early sign of disease is inflammation in the brain and the shift of resting glial cells to reactive astrocytes...
Autores principales: | Hay, Arielle J. D., Murphy, Tanner J., Popichak, Katriana A., Zabel, Mark D., Moreno, Julie A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800558/ https://www.ncbi.nlm.nih.gov/pubmed/36581683 http://dx.doi.org/10.1038/s41598-022-26628-7 |
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