Conformation specific antagonistic high affinity antibodies to the RON receptor kinase for imaging and therapy

The RON receptor tyrosine kinase is an exceptionally interesting target in oncology and immunology. It is not only overexpressed in a wide variety of tumors but also has been shown to be expressed on myeloid cells associated with tumor infiltration, where it serves to dampen tumour immune responses...

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Detalles Bibliográficos
Autores principales: Yu Koh, Xin, Koh, Xiao Hui, Spiegelberg, Diana, Jha, Preeti, Nestor, Marika, Hwang, Le-ann, Tan, Ban Xiong, Lane, David Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800565/
https://www.ncbi.nlm.nih.gov/pubmed/36581692
http://dx.doi.org/10.1038/s41598-022-26404-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800565/
https://www.ncbi.nlm.nih.gov/pubmed/36581692
http://dx.doi.org/10.1038/s41598-022-26404-7

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