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Conformation specific antagonistic high affinity antibodies to the RON receptor kinase for imaging and therapy
The RON receptor tyrosine kinase is an exceptionally interesting target in oncology and immunology. It is not only overexpressed in a wide variety of tumors but also has been shown to be expressed on myeloid cells associated with tumor infiltration, where it serves to dampen tumour immune responses...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800565/ https://www.ncbi.nlm.nih.gov/pubmed/36581692 http://dx.doi.org/10.1038/s41598-022-26404-7 |