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Metabolic contributions to neuronal deficits caused by genomic disruption of schizophrenia risk gene SETD1A

Regulation of neuronal metabolism during early brain development is crucial for directing synaptic plasticity and proper circuit formation. Alterations in neuronal glycolysis or mitochondrial function are associated with several neuropsychiatric disorders, including schizophrenia. Recently, loss-of-...

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Detalles Bibliográficos
Autores principales: Chong, Zheng-Shan, Khong, Zi Jian, Tay, Shermaine Huiping, Ng, Shi-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800576/
https://www.ncbi.nlm.nih.gov/pubmed/36581615
http://dx.doi.org/10.1038/s41537-022-00326-9