Cargando…
High p62 expression suppresses the NLRP1 inflammasome and increases stress resistance in cutaneous SCC cells
NLRP1 is the primary inflammasome sensor in human keratinocytes. Sensing of UVB radiation by NLRP1 is believed to underlie the induction of sunburn. Although constitutive NLRP1 activation causes skin inflammation and predisposes patients to the development of cutaneous SCCs, the NLRP1 pathway is sup...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800582/ https://www.ncbi.nlm.nih.gov/pubmed/36581625 http://dx.doi.org/10.1038/s41419-022-05530-0 |