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Machine learning methods for protein-protein binding affinity prediction in protein design

Protein-protein interactions govern a wide range of biological activity. A proper estimation of the protein-protein binding affinity is vital to design proteins with high specificity and binding affinity toward a target protein, which has a variety of applications including antibody design in immuno...

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Detalles Bibliográficos
Autores principales: Guo, Zhongliang, Yamaguchi, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800603/
https://www.ncbi.nlm.nih.gov/pubmed/36591334
http://dx.doi.org/10.3389/fbinf.2022.1065703