Canagliflozin promotes osteoblastic MC3T3-E1 differentiation via AMPK/RUNX2 and improves bone microarchitecture in type 2 diabetic mice

Individuals with type 2 diabetes mellitus (T2DM) have an increased risk of bone metabolic disorders and bone fracture due to disease progression and clinical treatment. The effect of sodium-glucose cotransporter 2 (SGLT2) inhibitors, now greatly prescribed for the treatment of T2DM, on bone metaboli...

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Detalles Bibliográficos
Autores principales: Song, Peiyang, Chen, Tianyi, Rui, Shunli, Duan, Xiaodong, Deng, Bo, Armstrong, David G., Ma, Yu, Deng, Wuquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800613/
https://www.ncbi.nlm.nih.gov/pubmed/36589840
http://dx.doi.org/10.3389/fendo.2022.1081039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800613/
https://www.ncbi.nlm.nih.gov/pubmed/36589840
http://dx.doi.org/10.3389/fendo.2022.1081039

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