Pumping the brakes: A noncanonical RNA-binding domain in FMRP stalls elongating ribosomes

Loss of function of the RNA-binding protein FMRP causes fragile X syndrome, the most common inherited form of intellectual disability and autism spectrum disorders. FMRP is suggested to modulate synaptic plasticity by regulating the synthesis of proteins involved in neuronal and synaptic function; h...

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Detalles Bibliográficos
Autor principal: Young-Baird, Sara K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800625/
https://www.ncbi.nlm.nih.gov/pubmed/36481269
http://dx.doi.org/10.1016/j.jbc.2022.102773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800625/
https://www.ncbi.nlm.nih.gov/pubmed/36481269
http://dx.doi.org/10.1016/j.jbc.2022.102773

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