The good Samaritan glutathione-S-transferase P1: An evolving relationship in nitric oxide metabolism mediated by the direct interactions between multiple effector molecules

Glutathione-S-transferases (GSTs) are phase II detoxification isozymes that conjugate glutathione (GSH) to xenobiotics and also suppress redox stress. It was suggested that GSTs have evolved not to enhance their GSH affinity, but to better interact with and metabolize cytotoxic nitric oxide (NO). Th...

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Detalles Bibliográficos
Autores principales: Russell, Tiffany M., Richardson, Des R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800640/
https://www.ncbi.nlm.nih.gov/pubmed/36563536
http://dx.doi.org/10.1016/j.redox.2022.102568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800640/
https://www.ncbi.nlm.nih.gov/pubmed/36563536
http://dx.doi.org/10.1016/j.redox.2022.102568

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