Size-advantage of monovalent nanobodies against the macrophage mannose receptor for deep tumor penetration and tumor-associated macrophage targeting

Rationale: Nanobodies (Nbs) have emerged as an elegant alternative to the use of conventional monoclonal antibodies in cancer therapy, but a detailed microscopic insight into the in vivo pharmacokinetics of different Nb formats in tumor-bearers is lacking. This is especially relevant for the recogni...

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Detalles Bibliográficos
Autores principales: Erreni, Marco, D'Autilia, Francesca, Avigni, Roberta, Bolli, Evangelia, Arnouk, Sana M., Movahedi, Kiavash, Debie, Pieterjan, Anselmo, Achille, Parente, Raffaella, Vincke, Cécile, van Leeuwen, Fijs W.B., Allavena, Paola, Garlanda, Cecilia, Mantovani, Alberto, Doni, Andrea, Hernot, Sophie, Van Ginderachter, Jo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800720/
https://www.ncbi.nlm.nih.gov/pubmed/36593955
http://dx.doi.org/10.7150/thno.77560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800720/
https://www.ncbi.nlm.nih.gov/pubmed/36593955
http://dx.doi.org/10.7150/thno.77560

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