Ablation of NLRP3 inflammasome attenuates muscle atrophy via inhibiting pyroptosis, proteolysis and apoptosis following denervation

Rationale: The inflammasome has been widely reported to be involved in various myopathies, but little is known about its role in denervated muscle. Here, we explored the role of NLRP3 inflammasome activation in experimental models of denervation in vitro and in vivo. Methods: Employing muscular NLRP...

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Detalles Bibliográficos
Autores principales: You, Zongqi, Huang, Xinying, Xiang, Yaoxian, Dai, Junxi, Xu, Lei, Jiang, Junjian, Xu, Jianguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800723/
https://www.ncbi.nlm.nih.gov/pubmed/36593964
http://dx.doi.org/10.7150/thno.74831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800723/
https://www.ncbi.nlm.nih.gov/pubmed/36593964
http://dx.doi.org/10.7150/thno.74831

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