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Stiff matrix induced srGAP2 tension gradients control migration direction in triple-negative breast cancer
Rationale: Cells migrating through interstitial matrix enables stiffening of the tumor micro-environment. To overcome the stiff resistance of extracellular matrix, aggressive cells require the extracellular mechanosensory activation and intracellular tension response. Mechanotransduction linker srGA...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800732/ https://www.ncbi.nlm.nih.gov/pubmed/36593959 http://dx.doi.org/10.7150/thno.77313 |