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Stiff matrix induced srGAP2 tension gradients control migration direction in triple-negative breast cancer

Rationale: Cells migrating through interstitial matrix enables stiffening of the tumor micro-environment. To overcome the stiff resistance of extracellular matrix, aggressive cells require the extracellular mechanosensory activation and intracellular tension response. Mechanotransduction linker srGA...

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Detalles Bibliográficos
Autores principales: Li, Chen, Zheng, Zihui, Wu, Xiang, Xie, Qiu, Liu, Ping, Hu, Yunfeng, Chen, Mei, Liu, Liming, Zhao, Wangxing, Chen, Linlin, Guo, Jun, Song, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800732/
https://www.ncbi.nlm.nih.gov/pubmed/36593959
http://dx.doi.org/10.7150/thno.77313