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Epigenetic drugs in somatostatin type 2 receptor radionuclide theranostics and radiation transcriptomics in mouse pheochromocytoma models

Pheochromocytomas and paragangliomas (PCCs/PGLs) are catecholamine-producing tumors. In inoperable and metastatic cases, somatostatin type 2 receptor (SSTR2) expression allows for peptide receptor radionuclide therapy with [(177)Lu]Lu-DOTA-TATE. Insufficient receptor levels, however, limit treatment...

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Detalles Bibliográficos
Autores principales: Ullrich, Martin, Richter, Susan, Liers, Josephine, Drukewitz, Stephan, Friedemann, Markus, Kotzerke, Jörg, Ziegler, Christian G., Nölting, Svenja, Kopka, Klaus, Pietzsch, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800739/
https://www.ncbi.nlm.nih.gov/pubmed/36593963
http://dx.doi.org/10.7150/thno.77918