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Acetate suppresses myocardial contraction via the short-chain fatty acid receptor GPR43

The heart has high energy requirements, with an estimated 40%–60% of myocardial ATP production derived from the oxidation of fatty acids under physiological conditions. However, the effect of short-chain fatty acids on myocardial contraction remains controversial, warranting further research. The pr...

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Detalles Bibliográficos
Autores principales: Jiang, Xuan, Zhang, Ying, Zhang, Huaxing, Zhang, Xiaoguang, Yin, Xiaopeng, Yuan, Fang, Wang, Sheng, Tian, Yanming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800787/
https://www.ncbi.nlm.nih.gov/pubmed/36589441
http://dx.doi.org/10.3389/fphys.2022.1111156