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The identities of insulin signaling pathway are affected by overexpression of Tau and its phosphorylation form
INTRODUCTION: Hyperphosphorylated Tau formed neurofibrillary tangles was one of the major neuropathological hallmarks of Alzheimer’s disease (AD). Dysfunctional insulin signaling in brain is involved in AD. However, the effect of Tau pathology on brain insulin resistance remains unclear. This study...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800792/ https://www.ncbi.nlm.nih.gov/pubmed/36589543 http://dx.doi.org/10.3389/fnagi.2022.1057281 |