Identification and mechanistic basis of non-ACE2 blocking neutralizing antibodies from COVID-19 patients with deep RNA sequencing and molecular dynamics simulations

Variants of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) continue to cause disease and impair the effectiveness of treatments. The therapeutic potential of convergent neutralizing antibodies (NAbs) from fully recovered patients has been explored in several early stages of novel drugs...

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Detalles Bibliográficos
Autores principales: Fredericks, Alger M., East, Kyle W., Shi, Yuanjun, Liu, Jinchan, Maschietto, Federica, Ayala, Alfred, Cioffi, William G., Cohen, Maya, Fairbrother, William G., Lefort, Craig T., Nau, Gerard J., Levy, Mitchell M., Wang, Jimin, Batista, Victor S., Lisi, George P., Monaghan, Sean F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800910/
https://www.ncbi.nlm.nih.gov/pubmed/36589229
http://dx.doi.org/10.3389/fmolb.2022.1080964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800910/
https://www.ncbi.nlm.nih.gov/pubmed/36589229
http://dx.doi.org/10.3389/fmolb.2022.1080964

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