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Intrinsic D614G and P681R/H mutations in SARS-CoV-2 VoCs Alpha, Delta, Omicron and viruses with D614G plus key signature mutations in spike protein alters fusogenicity and infectivity

The SARS-CoV-2 virus has been rapidly evolving over the time and the genetic variation has led to the generation of Variants of Concerns (VoC), which have shown increased fitness. These VoC viruses contain the key mutations in the spike protein which have allowed better survival and evasion of host...

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Detalles Bibliográficos
Autores principales: Khatri, Ritika, Siddqui, Gazala, Sadhu, Srikanth, Maithil, Vikas, Vishwakarma, Preeti, Lohiya, Bharat, Goswami, Abhishek, Ahmed, Shubbir, Awasthi, Amit, Samal, Sweety
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801140/
https://www.ncbi.nlm.nih.gov/pubmed/36583790
http://dx.doi.org/10.1007/s00430-022-00760-7