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Small Molecular Antimicrobial Ligands of YspD are Potential Therapeutic Agents Against Yersinia enterocolitica Infection

YspD is a hydrophilic translocator forming the platform for assemblage of functional translocon. Exposure to the extra-cellular milieu makes YspD a potential therapeutic target. DoGSiteScorer predicted best druggable pocket (P0) within YspD, encompassing predominantly the C-terminal helical bundles...

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Detalles Bibliográficos
Autores principales: Mandal, Debjani, Mukherjee, Raktim, Ghosh, Shrabana, Bachhawat, Tamanna, Dutta, Sneha, Das, Urmisha, Basu, Abhishek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801161/
https://www.ncbi.nlm.nih.gov/pubmed/36597505
http://dx.doi.org/10.1007/s40011-022-01443-2