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Germline mutations in high penetrance genes are associated with worse clinical outcomes in patients with non–small cell lung cancer

OBJECTIVE: To determine the frequency of pathogenic mutations in high-penetrance genes (HPGs) in patients with non–small cell lung cancer (NSCLC) and identify whether such mutations are associated with clinicopathologic outcomes. METHODS: Patients with NSCLC who had consented to participate in a lin...

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Detalles Bibliográficos
Autores principales: Krantz, Seth B., Zeeshan, Kanwal, Kuchta, Kristine M., Hensing, Thomas A., Mangold, Kathy A., Zheng, S. Lilly, Xu, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801288/
https://www.ncbi.nlm.nih.gov/pubmed/36590722
http://dx.doi.org/10.1016/j.xjon.2022.09.001