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Schwann Cells in the Aganglionic Colon of Hirschsprung Disease Can Generate Neurons for Regenerative Therapy

Cell therapy offers the potential to replace the missing enteric nervous system (ENS) in patients with Hirschsprung disease (HSCR) and to restore gut function. The Schwann cell (SC) lineage has been shown to generate enteric neurons pre- and post-natally. Here, we aimed to isolate SCs from the agang...

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Detalles Bibliográficos
Autores principales: Pan, Weikang, Rahman, Ahmed A, Stavely, Rhian, Bhave, Sukhada, Guyer, Richard, Omer, Meredith, Picard, Nicole, Goldstein, Allan M, Hotta, Ryo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801298/
https://www.ncbi.nlm.nih.gov/pubmed/36322091
http://dx.doi.org/10.1093/stcltm/szac076