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Indole and azaindole halogenation catalyzed by the RebH enzyme variant 3-LSR utilizing co-purified E. coli reductase

Biocatalytic C-H halogenation is becoming increasingly attractive due to excellent catalyst-controlled selectivity and environmentally benign reaction conditions. Significant efforts have been made on enzymatic halogenation of industrial arenes in a cost-effective manner. Here we report an unprecede...

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Detalles Bibliográficos
Autores principales: Li, Eunice Hui Yen, Sana, Barindra, Ho, Timothy, Ke, Ding, Ghadessy, Farid J., Duong, Hung A., Seayad, Jayasree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801302/
https://www.ncbi.nlm.nih.gov/pubmed/36588932
http://dx.doi.org/10.3389/fbioe.2022.1032707