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Engineering a Novel Self-Assembled Multi-siRNA Nanocaged Architecture with Controlled Enzyme-Mediated siRNA Release

[Image: see text] The RNA interference (RNAi) chemical and structural design space has evolved since its original definitions. Although this has led to the development of RNAi molecules that are starting to address the issues of silencing efficiency and delivery to target organs and cells, there is...

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Detalles Bibliográficos
Autores principales: Moreno, Pedro M. D., Cortinhas, João, Martins, Ana S., Pêgo, Ana P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801385/
https://www.ncbi.nlm.nih.gov/pubmed/36519952
http://dx.doi.org/10.1021/acsami.2c15086