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High-quality genome-scale metabolic network reconstruction of probiotic bacterium Escherichia coli Nissle 1917

BACKGROUND: Escherichia coli Nissle 1917 (EcN) is a probiotic bacterium used to treat various gastrointestinal diseases. EcN is increasingly being used as a chassis for the engineering of advanced microbiome therapeutics. To aid in future engineering efforts, our aim was to construct an updated meta...

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Detalles Bibliográficos
Autores principales: van ‘t Hof, Max, Mohite, Omkar S., Monk, Jonathan M., Weber, Tilmann, Palsson, Bernhard O., Sommer, Morten O. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801561/
https://www.ncbi.nlm.nih.gov/pubmed/36585633
http://dx.doi.org/10.1186/s12859-022-05108-9