USP13 regulates HMGB1 stability and secretion through its deubiquitinase activity

BACKGROUND: High mobility group box 1 (HMGB1) is a damage-associated molecular pattern (DAMP) molecule that plays a central role in innate immunity. HMGB1 acts as a late mediator of inflammation when actively secreted in response to inflammatory stimuli. Several post-translational modifications (PTM...

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Detalles Bibliográficos
Autores principales: Shin, Jaemin, Kim, Young Hun, Lee, Bin, Chang, Jae Ho, Choi, Hee Youn, Lee, Hoojung, Song, Ki Chan, Kwak, Man Sup, Choi, Ji Eun, Shin, Jeon-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801610/
https://www.ncbi.nlm.nih.gov/pubmed/36585612
http://dx.doi.org/10.1186/s10020-022-00596-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801610/
https://www.ncbi.nlm.nih.gov/pubmed/36585612
http://dx.doi.org/10.1186/s10020-022-00596-0

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