Cargando…

USP13 regulates HMGB1 stability and secretion through its deubiquitinase activity

BACKGROUND: High mobility group box 1 (HMGB1) is a damage-associated molecular pattern (DAMP) molecule that plays a central role in innate immunity. HMGB1 acts as a late mediator of inflammation when actively secreted in response to inflammatory stimuli. Several post-translational modifications (PTM...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shin, Jaemin, Kim, Young Hun, Lee, Bin, Chang, Jae Ho, Choi, Hee Youn, Lee, Hoojung, Song, Ki Chan, Kwak, Man Sup, Choi, Ji Eun, Shin, Jeon-Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801610/ https://www.ncbi.nlm.nih.gov/pubmed/36585612 http://dx.doi.org/10.1186/s10020-022-00596-0

Ejemplares similares

SARS-CoV-2 Infection Induces HMGB1 Secretion Through Post-Translational Modification and PANoptosis
por: Kwak, Man Sup, et al.
Publicado: (2023)

Secretory autophagy machinery and vesicular trafficking are involved in HMGB1 secretion
por: Kim, Young Hun, et al.
Publicado: (2020)

Immunological Significance of HMGB1 Post-Translational Modification and Redox Biology
por: Kwak, Man Sup, et al.
Publicado: (2020)

Deubiquitinase USP13 dictates MCL1 stability and sensitivity to BH3 mimetic inhibitors
por: Zhang, Shengzhe, et al.
Publicado: (2018)

Chloroquine Intervenes Nephrotoxicity of Nilotinib through Deubiquitinase USP13‐Mediated Stabilization of Bcl‐XL
por: Yan, Hao, et al.
Publicado: (2023)

Sulfatide Inhibits HMGB1 Secretion by Hindering Toll-Like Receptor 4 Localization Within Lipid Rafts
por: Kim, Hee Sue, et al.
Publicado: (2020)

Peroxiredoxin-mediated disulfide bond formation is required for nucleocytoplasmic translocation and secretion of HMGB1 in response to inflammatory stimuli
por: Kwak, Man Sup, et al.
Publicado: (2019)

Deubiquitinase USP17 Regulates Osteoblast Differentiation by Increasing Osterix Protein Stability
por: Kim, Myeong Ji, et al.
Publicado: (2023)

Stabilization of PIM Kinases in Hypoxia Is Mediated by the Deubiquitinase USP28
por: Toth, Rachel K., et al.
Publicado: (2022)

Deubiquitinase USP2 stabilizes the MRE11–RAD50–NBS1 complex at DNA double-strand break sites by counteracting the ubiquitination of NBS1
por: Kim, Hyunsup, et al.
Publicado: (2022)

The Deubiquitinase USP17 Regulates the Stability and Nuclear Function of IL-33
por: Ni, Yingmeng, et al.
Publicado: (2015)

The deubiquitinase USP21 stabilizes MEK2 to promote tumor growth
por: Li, Wenjuan, et al.
Publicado: (2018)

The deubiquitinase USP11 promotes ovarian cancer chemoresistance by stabilizing BIP
por: Zhu, Xiaolin, et al.
Publicado: (2021)

The Deubiquitinase USP13 Maintains Cancer Cell Stemness by Promoting FASN Stability in Small Cell Lung Cancer
por: Wang, Juhong, et al.
Publicado: (2022)

The deubiquitinase (DUB) USP13 promotes Mcl-1 stabilisation in cervical cancer
por: Morgan, Ethan L., et al.
Publicado: (2021)

Deubiquitinase USP29 Governs MYBBP1A in the Brains of Parkinson’s Disease Patients
por: Jo, Areum, et al.
Publicado: (2019)

Deubiquitinase USP1 enhances CCAAT/enhancer-binding protein beta (C/EBPβ) stability and accelerates adipogenesis and lipid accumulation
por: Kim, Myung Sup, et al.
Publicado: (2023)

Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2
por: Li, Wenyang, et al.
Publicado: (2020)

The deubiquitinase USP7 promotes HNSCC progression via deubiquitinating and stabilizing TAZ
por: Li, Jin, et al.
Publicado: (2022)

The deubiquitinase USP13 stabilizes the anti-inflammatory receptor IL-1R8/Sigirr to suppress lung inflammation
por: Li, Lian, et al.
Publicado: (2019)

Targeting deubiquitinase USP28 for cancer therapy
por: Wang, Xiaofang, et al.
Publicado: (2018)

HMGB1 orchestrates STING-mediated senescence via TRIM30α modulation in cancer cells
por: Lee, Je-Jung, et al.
Publicado: (2021)

Deubiquitinase USP47-stabilized splicing factor IK regulates the splicing of ATM pre-mRNA
por: Ka, Hye In, et al.
Publicado: (2020)

Reactive oxygen species induce Cys106-mediated anti-parallel HMGB1 dimerization that protects against DNA damage
por: Kwak, Man Sup, et al.
Publicado: (2021)

USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation
por: Palazón‐Riquelme, Pablo, et al.
Publicado: (2018)

The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer
por: Khan, Omar M., et al.
Publicado: (2018)

Identification of lipopolysaccharide-binding peptide regions within HMGB1 and their effects on subclinical endotoxemia in a mouse model
por: Youn, Ju Ho, et al.
Publicado: (2011)

Ablation of the deubiquitinase USP15 ameliorates nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
por: Baek, Jung-Hwan, et al.
Publicado: (2023)

Inhibition of the deubiquitinase USP10 induces degradation of SYK
por: Yang, Jing, et al.
Publicado: (2020)

Behavioral phenotyping of mice lacking the deubiquitinase USP2
por: Srikanta, Shashank Bangalore, et al.
Publicado: (2021)

USP48/USP31 Is a Nuclear Deubiquitinase that Potently Regulates Synapse Remodeling
por: Ma, Qi, et al.
Publicado: (2023)

Inflammasome-Dependent Peroxiredoxin 2 Secretion Induces the Classical Complement Pathway Activation
por: Park, Cheol Ho, et al.
Publicado: (2021)

Deubiquitinase USP13 regulates glycolytic reprogramming and progression in osteosarcoma by stabilizing METTL3/m(6)A/ATG5 axis
por: Wang, Ce, et al.
Publicado: (2023)

The deubiquitinase USP21 maintains the stemness of mouse embryonic stem cells via stabilization of Nanog
por: Jin, Jiali, et al.
Publicado: (2016)

USP1–UAF1 deubiquitinase complex stabilizes TBK1 and enhances antiviral responses
por: Yu, Zhongxia, et al.
Publicado: (2017)

USP52 acts as a deubiquitinase and promotes histone chaperone ASF1A stabilization
por: Yang, Shangda, et al.
Publicado: (2018)

Deubiquitinase USP35 as a novel mitotic regulator via maintenance of Aurora B stability
por: Park, Jinyoung, et al.
Publicado: (2018)

The Deubiquitinase USP4 Stabilizes Twist1 Protein to Promote Lung Cancer Cell Stemness
por: Li, Fengtian, et al.
Publicado: (2020)

The deubiquitinase USP6 affects memory and synaptic plasticity through modulating NMDA receptor stability
por: Zeng, Fanwei, et al.
Publicado: (2019)

Stabilization of SETD3 by deubiquitinase USP27 enhances cell proliferation and hepatocellular carcinoma progression
por: Zou, Tingting, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ce3glj6a89vfoodntg2kdl1i0j