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GIMAP7 induces oxidative stress and apoptosis of ovarian granulosa cells in polycystic ovary syndrome by inhibiting sonic hedgehog signalling pathway

Polycystic ovary syndrome (PCOS) is a gynaecological endocrine disease. The objective of the present study was to investigate the role of GTPase immunity-associated protein (GIMAP) 7 in PCOS. A PCOS rat model was established using dehydroepiandrosterone injection. The data showed that GIMAP7 was mai...

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Detalles Bibliográficos
Autores principales: Xu, Anran, Fan, Yuanyuan, Liu, Song, Sheng, Lianbing, Sun, Yanyan, Yang, Huijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801623/
https://www.ncbi.nlm.nih.gov/pubmed/36581994
http://dx.doi.org/10.1186/s13048-022-01092-z