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An explanation of how mutant and wild-type mitochondria might stably co-exist in inherited mitochondrial diseases
Mitochondria are cellular organelles of crucial relevance for the survival of metazoan organisms. Damage to the mitochondrial DNA can give rise to a variety of mitochondrial diseases and is thought also to be involved in the aging process. The fate of mtDNA mutants is controlled by their synthesis a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802247/ https://www.ncbi.nlm.nih.gov/pubmed/36714863 http://dx.doi.org/10.1093/pnasnexus/pgac192 |