Membrane-domain mutations in respiratory complex I impede catalysis but do not uncouple proton pumping from ubiquinone reduction

Respiratory complex I [NADH:ubiquinone (UQ) oxidoreductase] captures the free energy released from NADH oxidation and UQ reduction to pump four protons across an energy-transducing membrane and power ATP synthesis. Mechanisms for long-range energy coupling in complex I have been proposed from struct...

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Detalles Bibliográficos
Autores principales: Jarman, Owen D, Hirst, Judy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Biological, Health, and Medical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802314/
https://www.ncbi.nlm.nih.gov/pubmed/36712358
http://dx.doi.org/10.1093/pnasnexus/pgac276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802314/
https://www.ncbi.nlm.nih.gov/pubmed/36712358
http://dx.doi.org/10.1093/pnasnexus/pgac276

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