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Immunogenicity and protective efficacy of a pan-fungal vaccine in preclinical models of aspergillosis, candidiasis, and pneumocystosis

Invasive fungal infections cause over 1.5 million deaths worldwide. Despite increases in fungal infections as well as the numbers of individuals at risk, there are no clinically approved fungal vaccines. We produced a “pan-fungal” peptide, NXT-2, based on a previously identified vaccine candidate an...

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Detalles Bibliográficos
Autores principales: Rayens, Emily, Rabacal, Whitney, Willems, Hubertine M E, Kirton, Gabrielle M, Barber, James P, Mousa, Jarrod J, Celia-Sanchez, Brandi N, Momany, Michelle, Norris, Karen A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802316/
https://www.ncbi.nlm.nih.gov/pubmed/36712332
http://dx.doi.org/10.1093/pnasnexus/pgac248