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DNA fluctuations reveal the size and dynamics of topological domains

DNA supercoiling is a key regulatory mechanism that orchestrates DNA readout, recombination, and genome maintenance. DNA-binding proteins often mediate these processes by bringing two distant DNA sites together, thereby inducing (transient) topological domains. In order to understand the dynamics an...

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Detalles Bibliográficos
Autores principales: Vanderlinden, Willem, Skoruppa, Enrico, Kolbeck, Pauline J, Carlon, Enrico, Lipfert, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802373/
https://www.ncbi.nlm.nih.gov/pubmed/36712371
http://dx.doi.org/10.1093/pnasnexus/pgac268