CaMK4 overexpression in polycystic kidney disease promotes mTOR-mediated cell proliferation

Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive enlargement of fluid-filled cysts, causing nephron loss and a decline in renal function. Mammalian target of rapamycin (mTOR) is overactive in cyst-lining cells and contributes to abnormal cell proliferation and cys...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Daniel, Emily A, Metcalf, July, Dai, Yuqiao, Reif, Gail A, Wallace, Darren P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802383/
https://www.ncbi.nlm.nih.gov/pubmed/36002021
http://dx.doi.org/10.1093/jmcb/mjac050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802383/
https://www.ncbi.nlm.nih.gov/pubmed/36002021
http://dx.doi.org/10.1093/jmcb/mjac050

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