Sequence patterns and signatures: Computational and experimental discovery of amyloid-forming peptides

Screening amino acid sequence space via experiments to discover peptides that self-assemble into amyloid fibrils is challenging. We have developed a computational peptide assembly design (PepAD) algorithm that enables the discovery of amyloid-forming peptides. Discontinuous molecular dynamics (DMD)...

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Detalles Bibliográficos
Autores principales: Xiao, Xingqing, Robang, Alicia S, Sarma, Sudeep, Le, Justin V, Helmicki, Michael E, Lambert, Matthew J, Guerrero-Ferreira, Ricardo, Arboleda-Echavarria, Johana, Paravastu, Anant K, Hall, Carol K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Physical Sciences and Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802472/
https://www.ncbi.nlm.nih.gov/pubmed/36712347
http://dx.doi.org/10.1093/pnasnexus/pgac263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802472/
https://www.ncbi.nlm.nih.gov/pubmed/36712347
http://dx.doi.org/10.1093/pnasnexus/pgac263

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