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Eukaryotic gene regulation at equilibrium, or non?

Models of transcriptional regulation that assume equilibrium binding of transcription factors have been less successful at predicting gene expression from sequence in eukaryotes than in bacteria. This could be due to the non-equilibrium nature of eukaryotic regulation. Unfortunately, the space of po...

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Detalles Bibliográficos
Autores principales: Zoller, Benjamin, Gregor, Thomas, Tkačik, Gašper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802646/
https://www.ncbi.nlm.nih.gov/pubmed/36590072
http://dx.doi.org/10.1016/j.coisb.2022.100435