A homologous or variant booster vaccine after Ad26.COV2.S immunization enhances SARS-CoV-2–specific immune responses in rhesus macaques

Ad26.COV2.S has demonstrated durability and clinical efficacy against symptomatic COVID-19 in humans. In this study, we report the correlates of durability of humoral and cellular immune responses in 20 rhesus macaques immunized with single-shot Ad26.COV2.S and the immunogenicity of a booster shot a...

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Detalles Bibliográficos
Autores principales: He, Xuan, Aid, Malika, Chandrashekar, Abishek, Yu, Jingyou, McMahan, Katherine, Wegmann, Frank, Jacob-Dolan, Catherine, Maron, Jenny S., Atyeo, Caroline, Wan, Huahua, Sellers, Daniel, Liu, Jinyan, Lifton, Michelle, Gardner, Sarah, Bondzie, Esther A., Barrett, Julia, Ahmad, Kunza, Anioke, Tochi, Yalley-Ogunro, Jake, Muench, Jeanne, Goode, Adrienne, Andersen, Hanne, Lewis, Mark G., Alter, Galit, Schuitemaker, Hanneke, Zahn, Roland, Barouch, Dan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802654/
https://www.ncbi.nlm.nih.gov/pubmed/35191769
http://dx.doi.org/10.1126/scitranslmed.abm4996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802654/
https://www.ncbi.nlm.nih.gov/pubmed/35191769
http://dx.doi.org/10.1126/scitranslmed.abm4996

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