Cerebrospinal fluid neurofilament dynamic profiles predict cognitive progression in individuals with de novo Parkinson’s disease

BACKGROUND: Neurofilament light chain protein (NfL) in cerebrospinal fluid (CSF) reflects the severity of neurodegeneration, with its altered concentrations discovered in Parkinson’s disease (PD) and Parkinson’s disease dementia (PD-D). OBJECTIVE: To determine whether CSF NfL, a promising biomarker...

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Detalles Bibliográficos
Autores principales: Sheng, Ze-Hu, Ma, Ling-Zhi, Liu, Jia-Yao, Ou, Ya-Nan, Zhao, Bing, Ma, Ya-Hui, Tan, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802677/
https://www.ncbi.nlm.nih.gov/pubmed/36589544
http://dx.doi.org/10.3389/fnagi.2022.1061096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802677/
https://www.ncbi.nlm.nih.gov/pubmed/36589544
http://dx.doi.org/10.3389/fnagi.2022.1061096

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