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Kinesin-1 autoinhibition facilitates the initiation of dynein cargo transport

The functional significance of Kinesin-1 autoinhibition has been unclear. Kinesin-1 transports multiple cargoes including cytoplasmic dynein to microtubule plus ends. From a genetic screen for Aspergillus mutants defective in dynein-mediated early endosome transport, we identified a kinesin-1 mutati...

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Detalles Bibliográficos
Autores principales: Qiu, Rongde, Zhang, Jun, Xiang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802684/
https://www.ncbi.nlm.nih.gov/pubmed/36524956
http://dx.doi.org/10.1083/jcb.202205136