The yeast molecular chaperone, Hsp104, influences transthyretin aggregate formation

Patients with the fatal disorder Transthyretin Amyloidosis (ATTR) experience polyneuropathy through the progressive destruction of peripheral nervous tissue. In these patients, the transthyretin (TTR) protein dissociates from its functional tetrameric structure, misfolds, and aggregates into extrace...

Descripción completa

Detalles Bibliográficos
Autores principales: Knier, Adam S., Davis, Emily E., Buchholz, Hannah E., Dorweiler, Jane E., Flannagan, Lauryn E., Manogaran, Anita L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802906/
https://www.ncbi.nlm.nih.gov/pubmed/36590917
http://dx.doi.org/10.3389/fnmol.2022.1050472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802906/
https://www.ncbi.nlm.nih.gov/pubmed/36590917
http://dx.doi.org/10.3389/fnmol.2022.1050472

Ejemplares similares