Elevated retinal cGMP is not associated with elevated circulating cGMP levels in a canine model of retinitis pigmentosa

PURPOSE: To investigate whether raised levels of retinal cyclic guanosine monophosphate (cGMP) was reflected in plasma levels in PDE6A(-/-) dogs. MATERIALS AND METHODS: Retina was collected from 2-month-old wildtype dogs (PDE6A(+/+), N = 6), heterozygous dogs (PDE6A(+/-), N = 4) and affected dogs (P...

Descripción completa

Detalles Bibliográficos
Autores principales: Occelli, Laurence M., Sun, Kelian, Winkler, Paige A., Morgan, Brandy J., Petersen-Jones, Simon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803105/
https://www.ncbi.nlm.nih.gov/pubmed/36584140
http://dx.doi.org/10.1371/journal.pone.0279437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803105/
https://www.ncbi.nlm.nih.gov/pubmed/36584140
http://dx.doi.org/10.1371/journal.pone.0279437

Ejemplares similares