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A deep learning framework for classifying microglia activation state using morphology and intrinsic fluorescence lifetime data

Microglia are the immune cell in the central nervous system (CNS) and exist in a surveillant state characterized by a ramified form in the healthy brain. In response to brain injury or disease including neurodegenerative diseases, they become activated and change their morphology. Due to known corre...

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Detalles Bibliográficos
Autores principales: Mukherjee, Lopamudra, Sagar, Md Abdul Kader, Ouellette, Jonathan N., Watters, Jyoti J., Eliceiri, Kevin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803172/
https://www.ncbi.nlm.nih.gov/pubmed/36590907
http://dx.doi.org/10.3389/fninf.2022.1040008