Perfluorocarbons cause thrombocytopenia, changes in RBC morphology and death in a baboon model of systemic inflammation

A perfluorocarbon (PFC) investigated for treatment of traumatic brain injury (TBI) delivers oxygen to support brain function, but causes transient thrombocytopenia. TBI can cause acute inflammation with resulting thrombocytopenia; an interaction between the PFC effects and TBI inflammation might exa...

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Detalles Bibliográficos
Autores principales: Pidcoke, Heather F., Delacruz, Wilfred, Herzig, Maryanne C., Schaffer, Beverly S., Leazer, Sahar T., Fedyk, Chriselda G., Montogomery, Robbie K., Prat, Nicolas J., Parida, Bijaya K., Aden, James K., Scherer, Michael R., Reddick, Robert L., Shade, Robert E., Cap, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803179/
https://www.ncbi.nlm.nih.gov/pubmed/36584001
http://dx.doi.org/10.1371/journal.pone.0279694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803179/
https://www.ncbi.nlm.nih.gov/pubmed/36584001
http://dx.doi.org/10.1371/journal.pone.0279694

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