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Perfluorocarbons cause thrombocytopenia, changes in RBC morphology and death in a baboon model of systemic inflammation
A perfluorocarbon (PFC) investigated for treatment of traumatic brain injury (TBI) delivers oxygen to support brain function, but causes transient thrombocytopenia. TBI can cause acute inflammation with resulting thrombocytopenia; an interaction between the PFC effects and TBI inflammation might exa...
Autores principales: | Pidcoke, Heather F., Delacruz, Wilfred, Herzig, Maryanne C., Schaffer, Beverly S., Leazer, Sahar T., Fedyk, Chriselda G., Montogomery, Robbie K., Prat, Nicolas J., Parida, Bijaya K., Aden, James K., Scherer, Michael R., Reddick, Robert L., Shade, Robert E., Cap, Andrew P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803179/ https://www.ncbi.nlm.nih.gov/pubmed/36584001 http://dx.doi.org/10.1371/journal.pone.0279694 |
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