In vitro genome editing activity of Cas9 in somatic cells after random and transposon-based genomic Cas9 integration

Due to its close resemblance, the domesticated pig has proven to be a diverse animal model for biomedical research and genome editing tools have contributed to developing porcine models for several human diseases. By employing the CRISPR-Cas9 system, porcine embryos or somatic cells can be genetical...

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Detalles Bibliográficos
Autores principales: Söllner, Jenny-Helena, Sake, Hendrik Johannes, Frenzel, Antje, Lechler, Rita, Herrmann, Doris, Fuchs, Walter, Petersen, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803249/
https://www.ncbi.nlm.nih.gov/pubmed/36584049
http://dx.doi.org/10.1371/journal.pone.0279123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803249/
https://www.ncbi.nlm.nih.gov/pubmed/36584049
http://dx.doi.org/10.1371/journal.pone.0279123

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