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In vitro genome editing activity of Cas9 in somatic cells after random and transposon-based genomic Cas9 integration
Due to its close resemblance, the domesticated pig has proven to be a diverse animal model for biomedical research and genome editing tools have contributed to developing porcine models for several human diseases. By employing the CRISPR-Cas9 system, porcine embryos or somatic cells can be genetical...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803249/ https://www.ncbi.nlm.nih.gov/pubmed/36584049 http://dx.doi.org/10.1371/journal.pone.0279123 |