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The role of activated androgen receptor in cofilin phospho-regulation depends on the molecular subtype of TNBC cell line and actin assembly dynamics

Triple negative breast cancer (TNBC) is highly metastatic and of poor prognosis. Metastasis involves coordinated actin filament dynamics mediated by cofilin and associated proteins. Activated androgen receptor (AR) is believed to contribute to TNBC tumorigenesis. Our current work studied roles of ac...

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Detalles Bibliográficos
Autores principales: Tahtamouni, Lubna, Alzghoul, Ahmad, Alderfer, Sydney, Sun, Jiangyu, Ahram, Mamoun, Prasad, Ashok, Bamburg, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803305/
https://www.ncbi.nlm.nih.gov/pubmed/36584207
http://dx.doi.org/10.1371/journal.pone.0279746