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Optimal control of TGF-β to prevent formation of pulmonary fibrosis
In this paper, three optimal control problems are proposed to prevent forming lung fibrosis while control is transforming growth factor-β (TGF-β) in the myofibroblast diffusion process. Two diffusion equations for fibroblast and myofibroblast are mathematically formulated as the system’s dynamic, wh...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803315/ https://www.ncbi.nlm.nih.gov/pubmed/36584224 http://dx.doi.org/10.1371/journal.pone.0279449 |