VLA-4 suppression by senescence signals regulates meningeal immunity and leptomeningeal metastasis

Leptomeningeal metastasis is associated with dismal prognosis and has few treatment options. However, very little is known about the immune response to leptomeningeal metastasis. Here, by establishing an immunocompetent mouse model of breast cancer leptomeningeal metastasis, we found that tumor-spec...

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Detalles Bibliográficos
Autores principales: Li, Jiaqian, Huang, Di, Lei, Bingxi, Huang, Jingying, Yang, Linbing, Nie, Man, Su, Shicheng, Zhao, Qiyi, Wang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803356/
https://www.ncbi.nlm.nih.gov/pubmed/36484779
http://dx.doi.org/10.7554/eLife.83272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803356/
https://www.ncbi.nlm.nih.gov/pubmed/36484779
http://dx.doi.org/10.7554/eLife.83272

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