m(6)A modification of U6 snRNA modulates usage of two major classes of pre-mRNA 5’ splice site

Alternative splicing of messenger RNAs is associated with the evolution of developmentally complex eukaryotes. Splicing is mediated by the spliceosome, and docking of the pre-mRNA 5’ splice site into the spliceosome active site depends upon pairing with the conserved ACAGA sequence of U6 snRNA. In s...

Descripción completa

Detalles Bibliográficos
Autores principales: Parker, Matthew T, Soanes, Beth K, Kusakina, Jelena, Larrieu, Antoine, Knop, Katarzyna, Joy, Nisha, Breidenbach, Friedrich, Sherwood, Anna V, Barton, Geoffrey J, Fica, Sebastian M, Davies, Brendan H, Simpson, Gordon G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803359/
https://www.ncbi.nlm.nih.gov/pubmed/36409063
http://dx.doi.org/10.7554/eLife.78808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803359/
https://www.ncbi.nlm.nih.gov/pubmed/36409063
http://dx.doi.org/10.7554/eLife.78808

Ejemplares similares