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m(6)A modification of U6 snRNA modulates usage of two major classes of pre-mRNA 5’ splice site

Alternative splicing of messenger RNAs is associated with the evolution of developmentally complex eukaryotes. Splicing is mediated by the spliceosome, and docking of the pre-mRNA 5’ splice site into the spliceosome active site depends upon pairing with the conserved ACAGA sequence of U6 snRNA. In s...

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Detalles Bibliográficos
Autores principales:	Parker, Matthew T, Soanes, Beth K, Kusakina, Jelena, Larrieu, Antoine, Knop, Katarzyna, Joy, Nisha, Breidenbach, Friedrich, Sherwood, Anna V, Barton, Geoffrey J, Fica, Sebastian M, Davies, Brendan H, Simpson, Gordon G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Chromosomes and Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803359/ https://www.ncbi.nlm.nih.gov/pubmed/36409063 http://dx.doi.org/10.7554/eLife.78808

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